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Sonntag, William

One or more keywords matched the following items that are connected to Sonntag, William

Item Type	Name
Concept	Neurovascular Coupling
Concept	Kelch-Like ECH-Associated Protein 1
Concept	Superoxide Dismutase-1
Concept	Nogo Proteins
Concept	Nogo Receptor 1
Concept	Ampicillin
Concept	Serum Amyloid P-Component
Concept	Analysis of Variance
Concept	Androstadienes
Concept	Adrenocorticotropic Hormone
Concept	Angiotensin II
Concept	Angiotensin-Converting Enzyme Inhibitors
Concept	Animals
Concept	Animals, Newborn
Concept	Haplorhini
Concept	Age Factors
Concept	Aging
Concept	Anti-Inflammatory Agents, Non-Steroidal
Concept	Anti-Bacterial Agents
Concept	Alcohol Drinking
Concept	Ethanol
Concept	Alcoholism
Concept	Histocompatibility Antigens Class II
Concept	Antimetabolites
Concept	Antioxidants
Concept	Calcium
Concept	Energy Intake
Concept	Alzheimer Disease
Concept	Acetylcysteine
Concept	Capillary Permeability
Concept	Carbachol
Concept	Amino Acid Sequence
Concept	Actins
Concept	Activities of Daily Living
Concept	Acute-Phase Proteins
Concept	Carbon Dioxide
Concept	Carcinogens
Concept	African Americans
Concept	Axons
Concept	Blood Glucose
Concept	Blood Pressure
Concept	Blood-Brain Barrier
Concept	Body Temperature
Concept	Body Weight
Concept	Cardiovascular Physiological Phenomena
Concept	Base Sequence
Concept	Cartilage, Articular
Concept	Catalase
Concept	Catecholamines
Concept	Brain Injuries
Concept	Brain Mapping
Concept	Cattle
Concept	Benzilates
Concept	Bromodeoxyuridine
Concept	Cell Count
Concept	Cell Division
Concept	Cell Movement
Concept	beta-Endorphin
Concept	Cytotoxins
Concept	Bicuculline
Concept	Binding, Competitive
Concept	Biochemistry
Concept	Biology
Concept	C-Reactive Protein
Concept	Biophysics
Concept	Biotin
Concept	Dementia
Concept	Chromatography, High Pressure Liquid
Concept	Chronic Disease
Concept	Coronary Circulation
Concept	Corpus Callosum
Concept	Corticosterone
Concept	Corticotropin-Releasing Hormone
Concept	Circadian Rhythm
Concept	Depression
Concept	Crosses, Genetic
Concept	Dexamethasone
Concept	Clonidine
Concept	Evoked Potentials, Somatosensory
Concept	Exercise Test
Concept	Exercise Therapy
Concept	Extracellular Matrix
Concept	Collagen
Concept	Exudates and Transudates
Concept	Endorphins
Concept	Endothelium, Vascular
Concept	Complement C1
Concept	Enkephalin, Methionine
Concept	Enkephalins
Concept	Feedback
Concept	Femoral Artery
Concept	Enzyme Inhibitors
Concept	Enzyme-Linked Immunosorbent Assay
Concept	Dose-Response Relationship, Drug
Concept	Postural Balance
Concept	Fibroblasts
Concept	Drug Evaluation, Preclinical
Concept	Dwarfism
Concept	Dwarfism, Pituitary
Concept	Echocardiography
Concept	Estradiol
Concept	Estrogens
Concept	Estrus
Concept	Heterozygote
Concept	Guanosine
Concept	Hippocampus
Concept	Histocompatibility Antigens
Concept	Histocytochemistry
Concept	Gyrus Cinguli
Concept	Electrophoresis, Polyacrylamide Gel
Concept	Haloperidol
Concept	Homozygote
Concept	Health Status
Concept	Heart
Concept	Humans
Concept	Enalapril
Concept	Gene Expression Regulation
Concept	Heart Rate
Concept	Heat-Shock Proteins
Concept	Hybridization, Genetic
Concept	Genes, MHC Class II
Concept	Genetic Vectors
Concept	Hydrogen Peroxide
Concept	Hydrolysis
Concept	Heme Oxygenase (Decyclizing)
Concept	Hemodynamics
Concept	Geriatrics
Concept	Life Expectancy
Concept	Hemoglobinometry
Concept	Glial Fibrillary Acidic Protein
Concept	Gliosis
Concept	Lipoproteins, LDL
Concept	Liposomes
Concept	Glucose
Concept	Glucose Tolerance Test
Concept	Listeriosis
Concept	Listeria monocytogenes
Concept	Litter Size
Concept	Longevity
Concept	Glutamate Decarboxylase
Concept	Glutathione Peroxidase
Concept	Glutathione Synthase
Concept	Kidney Diseases
Concept	Kinetics
Concept	Lung Neoplasms
Concept	Lysine
Concept	Gonads
Concept	Lactation
Concept	Macaca fascicularis
Concept	Macaca mulatta
Concept	Magnetic Resonance Imaging
Concept	Major Histocompatibility Complex
Concept	Granuloma
Concept	Mammals
Concept	Growth
Concept	Growth Disorders
Concept	Inflammation
Concept	Learning
Concept	Mammary Neoplasms, Experimental
Concept	Infusions, Parenteral
Concept	Injections, Intraventricular
Concept	Injections, Subcutaneous
Concept	Neuromuscular Junction
Concept	Neuronal Plasticity
Concept	Insulin
Concept	Insulin Resistance
Concept	Insulin-Like Growth Factor I
Concept	Insulin-Like Growth Factor II
Concept	Levodopa
Concept	Luteinizing Hormone
Concept	Gonadotropin-Releasing Hormone
Concept	Multiple Organ Failure
Concept	Muscle Denervation
Concept	Muscle Proteins
Concept	Muscle, Smooth, Vascular
Concept	Nitric Oxide
Concept	Interleukins
Concept	Myelin Proteins
Concept	Myelin Sheath
Concept	Myocardial Contraction
Concept	Myocardium
Concept	Iodine Radioisotopes
Concept	Nucleic Acid Hybridization
Concept	Naloxone
Concept	Naltrexone
Concept	Narcotic Antagonists
Concept	Isoenzymes
Concept	Isoflavones
Concept	Obesity
Concept	Nephritis, Interstitial
Concept	Nerve Fibers, Myelinated
Concept	Nerve Regeneration
Concept	Methyldopa
Concept	Synaptic Transmission
Concept	Methyltyrosines
Concept	Mice, Inbred C3H
Concept	Mice, Inbred C57BL
Concept	Mice, Inbred ICR
Concept	Mice, Inbred Strains
Concept	Mice, Obese
Concept	Mice, Transgenic
Concept	Microcirculation
Concept	Phagocytes
Concept	Phenanthridines
Concept	Microscopy, Electron
Concept	Microspheres
Concept	Phenylalanine
Concept	Polyethylene Glycols
Concept	Polymers
Concept	Polyploidy
Concept	Mitochondria
Concept	Mitochondria, Heart
Concept	Models, Biological
Concept	Models, Neurological
Concept	Molecular Biology
Concept	Phosphatidylcholines
Concept	Phosphatidylethanolamines
Concept	Phosphatidylserines
Concept	Potassium
Concept	Monosaccharide Transport Proteins
Concept	Phosphopyruvate Hydratase
Concept	Morphine
Concept	Motion Pictures
Concept	Motor Cortex
Concept	Predictive Value of Tests
Concept	Pregnanolone
Concept	Piperazines
Concept	Piribedil
Concept	Pituitary Gland
Concept	Pituitary Gland, Anterior
Concept	Pituitary Gland, Posterior
Concept	Pituitary Hormones
Concept	Pituitary Hormones, Anterior
Concept	Regional Blood Flow
Concept	Renin-Angiotensin System
Concept	Parasympatholytics
Concept	Research Design
Concept	Retina
Concept	Pattern Recognition, Visual
Concept	Seawater
Concept	Seizures
Concept	Penicillamine
Concept	Seminal Vesicles
Concept	Pentobarbital
Concept	Endopeptidases
Concept	Risk Factors
Concept	RNA, Messenger
Concept	Sex Factors
Concept	Gonadal Steroid Hormones
Concept	Rodentia
Concept	Thymidine
Concept	Thymus Gland
Concept	Pulsatile Flow
Concept	Thyrotropin
Concept	Thyrotropin-Releasing Hormone
Concept	Tibial Fractures
Concept	Swimming
Concept	Swine
Concept	Synovial Membrane
Concept	Quality of Life
Concept	Quipazine
Concept	Rabbits
Concept	Radiation Injuries
Concept	Radiation Injuries, Experimental
Concept	Temperature
Concept	Radioimmunoassay
Concept	Radioligand Assay
Concept	Testosterone
Concept	Transducers, Pressure
Concept	Transduction, Genetic
Concept	Transfection
Concept	Random Allocation
Concept	Rats, Inbred BN
Concept	Rats, Inbred F344
Concept	Rats, Inbred Lew
Concept	Rats, Inbred SHR
Concept	Rats, Inbred Strains
Concept	Rats, Inbred WKY
Concept	Histocompatibility Antigens Class I
Concept	Exercise
Concept	Rats, Mutant Strains
Concept	Reaction Time
Concept	Receptors, Cell Surface
Concept	Receptors, GABA-A
Concept	Receptors, LHRH
Concept	Receptors, Immunologic
Concept	Receptor, Insulin
Concept	Receptors, Nicotinic
Concept	Receptors, Somatotropin
Concept	Recombinant Fusion Proteins
Concept	Fatty Acids, Omega-3
Concept	Transcriptional Activation
Concept	Down-Regulation
Concept	9,10-Dimethyl-1,2-benzanthracene
Concept	Dementia, Vascular
Concept	Echocardiography, Doppler
Concept	Immunoblotting
Concept	Blotting, Western
Concept	Antigens, CD
Concept	Electrophoresis, Gel, Two-Dimensional
Concept	Hominidae
Concept	Antigens, Differentiation, Myelomonocytic
Concept	Calcium Channels
Concept	Cell Adhesion Molecules
Concept	Stilbenes
Concept	Stochastic Processes
Concept	Genetic Therapy
Concept	Cohort Studies
Concept	Molecular Probes
Concept	Caenorhabditis elegans
Concept	Rats, Sprague-Dawley
Concept	DNA Probes
Concept	Interleukin-10
Concept	Genes, fos
Concept	Superoxides
Concept	Cyclooxygenase Inhibitors
Concept	Oxidants
Concept	Reactive Oxygen Species
Concept	Treatment Outcome
Concept	Vasoconstriction
Concept	Vasoconstrictor Agents
Concept	In Situ Hybridization
Concept	Sequence Analysis, DNA
Concept	Vasodilation
Concept	Vasodilator Agents
Concept	Vasomotor System
Concept	Pharmaceutical Vehicles
Concept	Receptors, Somatomedin
Concept	Receptors, Endothelin
Concept	Receptors, Glutamate
Concept	Receptors, Nerve Growth Factor
Concept	Vimentin
Concept	Culture Media, Conditioned
Concept	Receptor, IGF Type 1
Concept	Receptor, IGF Type 2
Concept	Intercellular Adhesion Molecule-1
Concept	Glycation End Products, Advanced
Concept	Neurotransmitter Agents
Concept	Oxidative Stress
Concept	Patch-Clamp Techniques
Concept	CD8-Positive T-Lymphocytes
Concept	Muscle, Skeletal
Concept	Muscle Fibers, Skeletal
Concept	Dentate Gyrus
Concept	Gene Expression Regulation, Developmental
Concept	Neovascularization, Physiologic
Concept	Cell Culture Techniques
Concept	Chemokine CCL2
Concept	Risk Assessment
Concept	Myelin-Associated Glycoprotein
Concept	Extracellular Matrix Proteins
Concept	Nitric Oxide Synthase
Concept	Vascular Cell Adhesion Molecule-1
Concept	Excitatory Amino Acid Agonists
Concept	Excitatory Amino Acid Antagonists
Concept	Statistics, Nonparametric
Concept	Transgenes
Concept	Hand Strength
Concept	Bacteremia
Concept	DNA Methylation
Concept	Maze Learning
Concept	Neurites
Concept	GTP-Binding Proteins
Concept	Amyloid beta-Protein Precursor
Concept	Stroke
Concept	tert-Butylhydroperoxide
Concept	Reverse Transcriptase Polymerase Chain Reaction
Concept	NAD(P)H Dehydrogenase (Quinone)
Concept	Response Elements
Concept	Hormone Replacement Therapy
Concept	Pericytes
Concept	Intracranial Hemorrhages
Concept	Myogenin
Concept	Gene Transfer Techniques
Concept	Leptin
Concept	Osteoarthritis, Knee
Concept	rhoA GTP-Binding Protein
Concept	Calcium Channels, L-Type
Concept	Middle Cerebral Artery
Concept	Matrix Metalloproteinase 2
Concept	Matrix Metalloproteinase 9
Concept	Receptors, AMPA
Concept	Gelatinases
Concept	Receptors, Tumor Necrosis Factor
Concept	Matrix Metalloproteinases
Concept	Receptor, Nerve Growth Factor
Concept	Animals, Genetically Modified
Concept	Mice, Knockout
Concept	alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Concept	Caloric Restriction
Concept	Caenorhabditis elegans Proteins
Concept	Excitatory Postsynaptic Potentials
Concept	Tissue Inhibitor of Metalloproteinase-2
Concept	Glutathione Disulfide
Concept	alpha-Methyltyrosine
Concept	Genistein
Concept	Chondrocytes
Concept	Prenatal Exposure Delayed Effects
Concept	GAP-43 Protein
Concept	Genes, p16
Concept	Primates
Concept	Probability
Concept	Receptor, TIE-2
Concept	Steroid Metabolism, Inborn Errors
Concept	Ribonuclease III
Concept	Progesterone
Concept	Prolactin
Concept	Fatty Acids, Omega-6
Concept	Promoter Regions, Genetic
Concept	Calcium Signaling
Concept	Receptor, Muscarinic M2
Concept	Receptor, Muscarinic M4
Concept	Receptor, Muscarinic M1
Concept	Muscle Development
Concept	Prospective Studies
Concept	Prostatic Neoplasms
Concept	Epigenesis, Genetic
Concept	Principal Component Analysis
Concept	Proto-Oncogene Proteins
Concept	5-Methylcytosine
Concept	Psychomotor Disorders
Concept	Psychomotor Performance
Concept	Shock, Septic
Concept	Large-Conductance Calcium-Activated Potassium Channel alpha Subunits
Concept	Sleep Deprivation
Concept	Toll-Like Receptor 4
Concept	Pituitary Adenylate Cyclase-Activating Polypeptide
Concept	Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide
Concept	Caveolin 1
Concept	Glucose Transporter Type 1
Concept	Glucose Transporter Type 3
Concept	Glucose Transporter Type 4
Concept	Mice
Concept	Rats
Concept	Peripheral Arterial Disease
Concept	Heme Oxygenase-1
Concept	GABA-A Receptor Antagonists
Concept	GPI-Linked Proteins
Concept	Somatomedins
Concept	Somatosensory Cortex
Concept	Somatostatin
Concept	Growth Hormone
Concept	Growth Hormone-Releasing Hormone
Concept	Purinergic P2Y Receptor Agonists
Concept	Space Perception
Concept	Specific Pathogen-Free Organisms
Concept	Ankle Brachial Index
Concept	Tritium
Concept	X-Ray Microtomography
Concept	Stem Cell Niche
Concept	Trypsin
Concept	Tumor Necrosis Factor-alpha
Concept	Tyrosine
Concept	Tyrosine 3-Monooxygenase
Concept	Spatial Memory
Concept	Purinergic P2Y Receptor Antagonists
Concept	Urinary Catheterization
Concept	Sensorimotor Cortex
Concept	Interleukin-6
Concept	Up-Regulation
Concept	Infusion Pumps, Implantable
Concept	Vascular Stiffness
Concept	RNA Interference
Concept	Gene Expression Regulation, Enzymologic
Concept	Lower Extremity
Concept	Multivariate Analysis
Concept	Confidence Intervals
Concept	Linear Models
Concept	Logistic Models
Concept	Odds Ratio
Concept	Survival Analysis
Concept	Case-Control Studies
Concept	Bone Marrow Transplantation
Concept	Transcriptome
Concept	MicroRNAs
Concept	Intercellular Signaling Peptides and Proteins
Concept	Walking
Concept	Free Radical Scavengers
Concept	Receptors, N-Methyl-D-Aspartate
Concept	Cytokines
Concept	Interleukin-8
Concept	Amyloid beta-Peptides
Concept	Guanosine 5'-O-(3-Thiotriphosphate)
Concept	Ultrasonography, Doppler, Transcranial
Concept	Hydroxyl Radical
Concept	Organogenesis
Concept	Adaptor Proteins, Signal Transducing
Concept	Cell Proliferation
Concept	Presynaptic Terminals
Concept	Green Fluorescent Proteins
Concept	History, 20th Century
Concept	Bivalvia
Concept	Mercenaria
Concept	RANK Ligand
Concept	Long-Term Potentiation
Concept	Vascular Endothelial Growth Factor Receptor-2
Concept	Mechanotransduction, Cellular
Concept	Sarcoplasmic Reticulum Calcium-Transporting ATPases
Concept	Somatostatin-28
Concept	Interleukin-1beta
Concept	Calcium-Calmodulin-Dependent Protein Kinases
Concept	Janus Kinase 2
Concept	Genes, Reporter
Concept	Interleukin-12 Subunit p40
Concept	NADPH Oxidases
Concept	Spectroscopy, Near-Infrared
Concept	Early Diagnosis
Concept	Vascular Endothelial Growth Factor A
Concept	Computational Biology
Concept	NG-Nitroarginine Methyl Ester
Concept	Endothelin-1
Concept	Amyloid Precursor Protein Secretases
Concept	Human Growth Hormone
Concept	Angiopoietin-1
Concept	Angiopoietin-2
Concept	TRPC Cation Channels
Concept	Atherosclerosis
Concept	Hindlimb Suspension
Concept	Neocortex
Concept	Mossy Fibers, Hippocampal
Concept	Cytoprotection
Concept	STAT3 Transcription Factor
Concept	Mice, 129 Strain
Concept	Gene Expression Profiling
Concept	Receptor, trkA
Concept	Pulse Wave Analysis
Concept	Quantitative Structure-Activity Relationship
Concept	Carcinogenesis
Concept	Fetal Alcohol Spectrum Disorders
Concept	Protein Tyrosine Phosphatases, Non-Receptor
Concept	Models, Animal
Concept	Collagen Type IV
Concept	Receptors, Purinergic P2Y1
Concept	Microarray Analysis
Concept	Tissue Culture Techniques
Concept	Microscopy, Electron, Transmission
Concept	Caspase 3
Concept	Caspase 8
Concept	Proteasome Endopeptidase Complex
Concept	ADAM Proteins
Concept	Inhibitor of Differentiation Proteins
Concept	Gene Knockdown Techniques
Concept	Actigraphy
Concept	Nitric Oxide Synthase Type I
Concept	Nitric Oxide Synthase Type III
Concept	CA1 Region, Hippocampal
Concept	Sirtuin 1
Concept	CA3 Region, Hippocampal
Concept	Real-Time Polymerase Chain Reaction
Concept	Early Medical Intervention
Concept	Fitness Trackers
Concept	Microvascular Rarefaction
Concept	TRPC6 Cation Channel
Concept	NADPH Oxidase 2
Concept	Aorta
Concept	Apurinic Acid
Concept	Arginine
Concept	Arthritis, Experimental
Concept	Ascorbic Acid
Concept	Autoradiography
Concept	Cell Survival
Concept	Cell Transformation, Neoplastic
Concept	Cerebral Cortex
Concept	Cerebral Hemorrhage
Concept	Cerebral Infarction
Concept	Brain Ischemia
Concept	Cerebrovascular Circulation
Concept	Cerebrovascular Disorders
Concept	Chick Embryo
Concept	Diaphragm
Concept	Diastole
Concept	Dietary Fats
Concept	Dietary Fats, Unsaturated
Concept	Diptera
Concept	Disease
Concept	Disease Models, Animal
Concept	DNA, Circular
Concept	Fluorescent Antibody Technique
Concept	Free Radicals
Concept	Gait
Concept	Gamma Rays
Concept	Hydroxyeicosatetraenoic Acids
Concept	Hypercapnia
Concept	Hyperglycemia
Concept	Hypothalamic Hormones
Concept	Hypothalamo-Hypophyseal System
Concept	Hypothalamus
Concept	Hypothalamus, Anterior
Concept	Hypothalamus, Middle
Concept	Immune Sera
Concept	Immunization, Passive
Concept	Immunohistochemistry
Concept	Immunologic Memory
Concept	Membrane Fluidity
Concept	Membrane Glycoproteins
Concept	Membrane Lipids
Concept	Membrane Potentials
Concept	Memory
Concept	Memory Disorders
Concept	Memory, Short-Term
Concept	Metals
Concept	Oklahoma
Concept	Oligodendroglia
Concept	Organ Culture Techniques
Concept	Organ Specificity
Concept	Organ Size
Concept	Osteoarthritis
Concept	Osteoporosis
Concept	Oxidation-Reduction
Concept	Oxygen
Concept	Fenclonine
Academic Article	Cerebral microvascular rarefaction induced by whole brain radiation is reversible by systemic hypoxia in mice.
Academic Article	Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia.
Academic Article	Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression.
Academic Article	Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response.
Academic Article	Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta.
Academic Article	Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging.
Academic Article	Growth hormone and IGF-1 deficiency exacerbate high-fat diet-induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging.
Academic Article	Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging.
Academic Article	Regional changes in CNS and retinal glycerophospholipid profiles with age: a molecular blueprint.
Academic Article	Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation-induced impairment of neurovascular coupling responses protecting cognitive function in mice.
Academic Article	Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation.
Academic Article	Age-related decline in peripheral vascular health predicts cognitive impairment.
Academic Article	Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research.
Academic Article	Insulin-like growth factor-1 selectively increases glucose utilization in brains of aged animals.
Academic Article	The effects of growth hormone and IGF-1 deficiency on cerebrovascular and brain ageing.
Academic Article	Caloric restricted male rats demonstrate fewer synapses in layer 2 of sensorimotor cortex.
Academic Article	Of worms, flies, dwarfs, and things that go bump in the night.
Academic Article	Biomarkers of aging: from primitive organisms to humans.
Academic Article	Growth, metabolism, and blood pressure disturbances during aging in transgenic rats with altered brain renin-angiotensin systems.
Academic Article	Dendritic stability in a model of adult-onset IGF-I deficiency.
Academic Article	Growth hormone replacement attenuates diastolic dysfunction and cardiac angiotensin II expression in senescent rats.
Academic Article	Effects of short-term treadmill exercise training or growth hormone supplementation on diastolic function and exercise tolerance in old rats.
Academic Article	How age impairs the response of the neuromuscular junction to nerve transection and repair: An experimental study in rats.
Academic Article	Plasma growth hormones, P300 event-related potential and test of variables of attention (TOVA) are important neuroendocrinological predictors of early cognitive decline in a clinical setting: evidence supported by structural equation modeling (SEM) parameter estimates.
Academic Article	Early-onset GH deficiency results in spatial memory impairment in mid-life and is prevented by GH supplementation.
Academic Article	Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2.
Academic Article	Impaired bladder function in aging male rats.
Academic Article	An assay for RNA oxidation induced abasic sites using the Aldehyde Reactive Probe.
Academic Article	Extreme longevity is associated with increased resistance to oxidative stress in Arctica islandica, the longest-living non-colonial animal.
Academic Article	Whole brain radiation-induced impairments in learning and memory are time-sensitive and reversible by systemic hypoxia.
Academic Article	Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients.
Academic Article	Treatment with the cytochrome P450 ?-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats.
Academic Article	Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.
Academic Article	Impaired vascular endothelial growth factor A and inflammation in patients with peripheral artery disease.
Academic Article	Whole brain radiation-induced cognitive impairment: pathophysiological mechanisms and therapeutic targets.
Academic Article	Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice.
Academic Article	Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats.
Academic Article	Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.
Academic Article	Role of NADPH oxidase in radiation-induced pro-oxidative and pro-inflammatory pathways in mouse brain.
Academic Article	Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-ß uptake in astrocytes.
Academic Article	Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice.
Academic Article	Accelerated decline in cognition in a mouse model of increased oxidative stress.
Academic Article	Neuroinvasive Listeria monocytogenes infection triggers accumulation of brain CD8+ tissue-resident memory T cells in a miR-155-dependent fashion.
Academic Article	The effect of complete Freund--adjuvant on chronic proliferating inflammation in an experimental granuloma model.
Academic Article	Effects of aging and dietary restriction on tissue protein synthesis: relationship to plasma insulin-like growth factor-1.
Academic Article	Increased pituitary response to somatostatin in aging male rats: relationship to somatostatin receptor number and affinity.
Academic Article	Diminished insulin-like growth factor-1 levels after chronic ethanol: relationship to pulsatile growth hormone release.
Academic Article	Pituitary growth hormone and hypothalamic somatostatin in young female rats versus old constant estrous female rats.
Academic Article	Hypothalamic hypophysiotropic hormones and neurotransmitter regulation: current views.
Academic Article	Effects of CNS active drugs and somatostatin antiserum on growth hormone release in young and old male rats.
Academic Article	L-dopa restores amplitude of growth hormone pulses in old male rats to that observed in young male rats.
Academic Article	Cell fusion as a mechanism for the formation of giant cells (Langhans' type). Autoradiographic findings in autoimmune tubulo-interstitial nephritis of the rat.
Academic Article	Decreases in growth hormone receptor signal transduction contribute to the decline in insulin-like growth factor I gene expression with age.
Academic Article	Long-term suppression of insulin-like growth factor-1 in rats after in utero ethanol exposure: relationship to somatic growth.
Academic Article	Moderate caloric restriction prevents the age-related decline in growth hormone receptor signal transduction.
Academic Article	Expression of insulin-like growth factor-1 (IGF-1) and IGF-binding protein 2 (IGF-BP2) in the hippocampus following cytotoxic lesion of the dentate gyrus.
Academic Article	Models of growth hormone and IGF-1 deficiency: applications to studies of aging processes and life-span determination.
Academic Article	Physical performance and longevity in aged rats.
Academic Article	A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan.
Academic Article	Growth hormone, insulin-like growth factor-1 and the aging cardiovascular system.
Academic Article	Differential effects of aging and insulin-like growth factor-1 on synapses in CA1 of rat hippocampus.
Academic Article	Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span.
Academic Article	Effects of chronic growth hormone and insulin-like growth factor 1 deficiency on osteoarthritis severity in rat knee joints.
Academic Article	Spatial learning and memory deficits after whole-brain irradiation are associated with changes in NMDA receptor subunits in the hippocampus.
Academic Article	Growth hormone and aging: Regulation, signal transduction and replacement therapy.
Academic Article	Mechanisms of vascular aging: new perspectives.
Academic Article	Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment.
Academic Article	Growth hormone modulates hippocampal excitatory synaptic transmission and plasticity in old rats.
Academic Article	Irradiation alters MMP-2/TIMP-2 system and collagen type IV degradation in brain.
Academic Article	Testing predictions of the oxidative stress hypothesis of aging using a novel invertebrate model of longevity: the giant clam (Tridacna derasa).
Academic Article	Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells.
Academic Article	Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial cells: role of increased DNA damage and decreased DNA repair capacity in microvascular radiosensitivity.
Academic Article	Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice.
Academic Article	Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications.
Academic Article	Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats.
Academic Article	Greater endothelial apoptosis and oxidative stress in patients with peripheral artery disease.
Academic Article	Metabolic enrichment of omega-3 polyunsaturated fatty acids does not reduce the onset of idiopathic knee osteoarthritis in mice.
Academic Article	Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells.
Academic Article	Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex.
Academic Article	The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer.
Academic Article	Association between daily walking and antioxidant capacity in patients with symptomatic peripheral artery disease.
Academic Article	Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype.
Academic Article	Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.
Academic Article	Distribution of insulin-like growth factor 1 (IGF-1) and 2 (IGF-2) receptors in the hippocampal formation of rats and mice.
Academic Article	Attenuation of Fos-like immunoreactivity induced by a single electroconvulsive shock in brains of aging mice.
Academic Article	Increased secretion of somatostatin-28 from hypothalamic neurons of aged rats in vitro.
Academic Article	Effect of CNS-active drugs on TRH-induced prolactin release.
Academic Article	Mediation by gonadal steroids of plasma beta-endorphin and LH in castrated female and male rats.
Academic Article	Diminished diurnal secretion of adrenocorticotropin (ACTH), but not corticosterone, in old male rats: possible relation to increased adrenal sensitivity to ACTH in vivo.
Academic Article	Chronic ethanol feeding inhibits plasma levels of insulin-like growth factor-1.
Academic Article	Immunoreactive beta-endorphin in the plasma, pituitary and hypothalamus of young and old male rats.
Academic Article	Immunoreactive beta-endorphin in the plasma, pituitary and hypothalamus of young female rats on the day of estrus and intact and chronically castrated old constant estrous female rats.
Academic Article	Reduced ability of old male rats to release ACTH and corticosterone in response to CRF administration.
Academic Article	Decreased ability of old male rats to secrete luteinizing hormone (LH) is not due to alterations in pituitary LH-releasing hormone receptors.
Academic Article	Effects of ovariectomy and steroid replacement on hypothalamic LHRH content in aging female rats.
Academic Article	Impaired ability of old male rats to secrete growth hormone in vivo but not in vitro in response to hpGRF(1-44).
Academic Article	Comparison of the effects of central acting drugs on prolactin release in young and old male rats.
Academic Article	Effect of in utero ethanol exposure on the postnatal ontogeny of insulin-like growth factor-1, and type-1 and type-2 insulin-like growth factor receptors in the rat brain.
Academic Article	Growth hormone-induced nuclear translocation of Stat-3 decreases with age: modulation by caloric restriction.
Academic Article	Distribution and levels of insulin-like growth factor I mRNA across the life span in the Brown Norway x Fischer 344 rat brain.
Academic Article	Pleiotropic effects of growth hormone and insulin-like growth factor (IGF)-1 on biological aging: inferences from moderate caloric-restricted animals.
Academic Article	Age and insulin-like growth factor-1 modulate N-methyl-D-aspartate receptor subtype expression in rats.
Academic Article	Chronic [D-Ala2]-growth hormone-releasing hormone administration attenuates age-related deficits in spatial memory.
Academic Article	Growth hormone increases regional coronary blood flow and capillary density in aged rats.
Academic Article	Growth hormone-deficient dwarf animals are resistant to dimethylbenzanthracine (DMBA)-induced mammary carcinogenesis.
Academic Article	Growth hormone treatment attenuates age-related changes in hippocampal short-term plasticity and spatial learning.
Academic Article	Growth hormone administration to aged animals reduces disulfide glutathione levels in hippocampus.
Academic Article	Lifelong caloric restriction and interleukin-6 secretion from adipose tissue: effects on physical performance decline in aged rats.
Academic Article	Adult-onset deficiency in growth hormone and insulin-like growth factor-I alters oligodendrocyte turnover in the corpus callosum.
Academic Article	Vasoprotective effects of life span-extending peripubertal GH replacement in Lewis dwarf rats.
Academic Article	Mitochondria and aging in the vascular system.
Academic Article	Quantification of oxidized levels of specific RNA species using an aldehyde reactive probe.
Academic Article	Circulating IGF1 regulates hippocampal IGF1 levels and brain gene expression during adolescence.
Academic Article	Muscarinic receptor/G-protein coupling is reduced in the dorsomedial striatum of cognitively impaired aged rats.
Academic Article	Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies.
Academic Article	Resistance to genotoxic stresses in Arctica islandica, the longest living noncolonial animal: is extreme longevity associated with a multistress resistance phenotype?
Academic Article	Increased hippocampal NgR1 signaling machinery in aged rats with deficits of spatial cognition.
Academic Article	Insulin-like growth factor-1 in CNS and cerebrovascular aging.
Academic Article	Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease.
Academic Article	Positive Feedback by Ovarian Hormones on Prolactin and LH in Old Versus Young Female Rats.
Academic Article	Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase.
Academic Article	Gender and racial differences in endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease.
Academic Article	Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.
Academic Article	Endothelial Cell Inflammation and Antioxidant Capacity are Associated With Exercise Performance and Microcirculation in Patients With Symptomatic Peripheral Artery Disease.
Academic Article	Aging impairs myogenic adaptation to pulsatile pressure in mouse cerebral arteries.
Academic Article	IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging.
Academic Article	Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice.
Academic Article	Maintenance by L-DOPA treatment of estrous cycles and LH response to estrogen in aging female rats.
Academic Article	Suppression by naloxone of rise in plasma growth hormone and prolactin induced by sucking.
Academic Article	Differential effects of IGF-1 deficiency during the life span on structural and biomechanical properties in the tibia of aged mice.
Academic Article	Effects of age and insulin-like growth factor-1 on rat neurotrophin receptor expression after nerve injury.
Academic Article	GeroScience: understanding the interaction of processes of aging and chronic diseases.
Academic Article	Reproduction in aging normal and neonatally androgenized female rats.
Academic Article	Reduced ability of naloxone to stimulate LH and testosterone release in aging male rats; possible relation to increase in hypothalamic met5-enkephalin.
Academic Article	Decreased pulsatile release of growth hormone in old male rats.
Academic Article	Age-related focal loss of contractile vascular smooth muscle cells in retinal arterioles is accelerated by caveolin-1 deficiency.
Academic Article	Comparison of protein synthesis in brain and peripheral tissue during aging. Relationship to insulin-like growth factor-1 and type 1 IGF receptors.
Academic Article	Interleukin 6 reduces allopregnanolone synthesis in the brain and contributes to age-related cognitive decline in mice.
Academic Article	Insulin-like growth factor-1 ameliorates age-related behavioral deficits.
Academic Article	Effect of age and caloric restriction on insulin receptor binding and glucose transporter levels in aging rats.
Academic Article	Chronic caloric restriction alters muscle membrane fatty acid content.
Academic Article	Age-related synaptic changes in sensorimotor cortex of the Brown Norway X fischer 344 rat.
Academic Article	Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease.
Academic Article	Angiotensin-converting enzyme inhibition, body composition, and physical performance in aged rats.
Academic Article	Functional characterization of des-IGF-1 action at excitatory synapses in the CA1 region of rat hippocampus.
Academic Article	Adult-onset deficiency in growth hormone and insulin-like growth factor-I decreases survival of dentate granule neurons: insights into the regulation of adult hippocampal neurogenesis.
Academic Article	Growth hormone and IGF-I modulate local cerebral glucose utilization and ATP levels in a model of adult-onset growth hormone deficiency.
Academic Article	Basal and hypercapnia-altered cerebrovascular perfusion predict mild cognitive impairment in aging rodents.
Academic Article	Effect of locally delivered IGF-1 on nerve regeneration during aging: an experimental study in rats.
Academic Article	Aging attenuates radiation-induced expression of pro-inflammatory mediators in rat brain.
Academic Article	Aging-related kidney damage is associated with a decrease in klotho expression and an increase in superoxide production.
Academic Article	Free radical production, antioxidant capacity, and oxidative stress response signatures in fibroblasts from Lewis dwarf rats: effects of life span-extending peripubertal GH treatment.
Academic Article	Early-onset growth hormone deficiency results in diastolic dysfunction in adult-life and is prevented by growth hormone supplementation.
Academic Article	Mitochondrial protection by resveratrol.
Academic Article	Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment.
Academic Article	Testing the oxidative stress hypothesis of aging in primate fibroblasts: is there a correlation between species longevity and cellular ROS production?
Academic Article	RNA oxidation catalyzed by cytochrome c leads to its depurination and cross-linking, which may facilitate cytochrome c release from mitochondria.
Academic Article	Expression of NgR1-antagonizing proteins decreases with aging and cognitive decline in rat hippocampus.
Academic Article	Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension.
Academic Article	Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in ß-amyloid generation and Alzheimer's disease.
Academic Article	A heart that beats for 500 years: age-related changes in cardiac proteasome activity, oxidative protein damage and expression of heat shock proteins, inflammatory factors, and mitochondrial complexes in Arctica islandica, the longest-living noncolonial animal.
Academic Article	IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice.
Academic Article	Aging Exacerbates Pressure-Induced Mitochondrial Oxidative Stress in Mouse Cerebral Arteries.
Academic Article	Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection.
Academic Article	IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms.
Academic Article	Bisulfite oligonucleotide-capture sequencing for targeted base- and strand-specific absolute 5-methylcytosine quantitation.
Academic Article	IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis.
Academic Article	IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan.
Academic Article	Endothelial Cell Inflammation and Antioxidant Capacity are Associated With 6-Minute Walk Performance in Patients With Symptomatic Peripheral Artery Disease.
Academic Article	Simultaneous assessment of cognitive function, circadian rhythm, and spontaneous activity in aging mice.
Academic Article	Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice.
Academic Article	The influence of D-penicillamine on cell proliferation. I. Quantitative investigations during an acute exudative inflammation in a model granuloma.
Academic Article	The influence of D-penicillamine on cell proliferation. II. Quantitative investigations during a chronic proliferative inflammation in a model granuloma.
Academic Article	Growth hormone restores protein synthesis in skeletal muscle of old male rats.
Academic Article	Moderate caloric restriction increases type 1 IGF receptors and protein synthesis in aging rats.
Academic Article	Caloric restriction decreases age-dependent accumulation of the glycoxidation products, N epsilon-(carboxymethyl)lysine and pentosidine, in rat skin collagen.
Academic Article	Ethanol suppresses growth hormone-mediated cellular responses in liver slices.
Academic Article	Decreases in cerebral microvasculature with age are associated with the decline in growth hormone and insulin-like growth factor 1.
Grant	TNF ALPHA REG OF THE GROWTH HORMONE/IGF-1 AXIS WITH AGE
Grant	Cognitive Decline &Protein Expression Profiles in Aging
Grant	Biology of Aging Sessions at Meetings of The Gerontological Society of America
Grant	CHRONIC ETHANOL AND INSULIN-LIKE GROWTH FACTORS
Grant	TESTING THE ABILITY OF NOVEL ASSAYS OF RESILIENCE TO PREDICT LIFESPAN
Grant	Effects of Radiation on Brain Microvasculature and Cognition
Grant	NOVEL APPROACHES FOR REGULATION OF IGF-1 LEVELS THROUGHOUT THE LIFESPAN
Grant	GROWTH HORMONE (GH) AND GH-DEPENDENT BIOMARKERS OF AGING
Grant	GEROSCIENCE TRAINING PROGRAM IN OKLAHOMA
Grant	Growth Hormone, IGF-1 and Age-related Pathogenesis
Grant	Growth Hormone &IGF-1 in CNS and Cerebrovascular Aging
Grant	REGULATION OF GROWTH HORMONE SECRETION IN AGING RATS
Grant	CHRONIC ETHANOL, GROWTH HORMONE AND PROTEIN SYNTHESIS
Grant	Oklahoma Nathan Shock Center of Excellence in Basic Biology of Aging
Academic Article	IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging.
Academic Article	Oklahoma Nathan Shock Aging Center - assessing the basic biology of aging from genetics to protein and function.
Academic Article	Measuring Behavior in the Home Cage: Study Design, Applications, Challenges, and Perspectives.
Academic Article	Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses.
Academic Article	Sleep deprivation alters task-related changes in functional connectivity of the frontal cortex: A near-infrared spectroscopy study.
Academic Article	Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype.
Academic Article	Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging.
Academic Article	[Polyploidisation - a phenomenon of aging? (author's transl)].
Academic Article	Systemic Listeria monocytogenes infection in aged mice induces long-term neuroinflammation: the role of miR-155.
Academic Article	Decreased lifespan in female "Munchkin" actors from the cast of the 1939 film version of The Wizard of Oz does not support the hypothesis linking hypopituitary dwarfism to longevity.
Academic Article	Measurements of cerebral microvascular blood flow, oxygenation, and morphology in a mouse model of whole-brain irradiation-induced cognitive impairment by two-photon microscopy and optical coherence tomography: evidence for microvascular injury in the cerebral white matter.
Academic Article	Cognitive heterogeneity reveals molecular signatures of age-related impairment.
Academic Article	Sex differences in brain functional connectivity of hippocampus in mild cognitive impairment.
Academic Article	Progressive cognitive impairment after recovery from neuroinvasive and non-neuroinvasive Listeria monocytogenes infection.
Academic Article	Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain.
Academic Article	Sex difference in brain functional connectivity of hippocampus in Alzheimer's disease.
Academic Article	Impaired Neurovascular Coupling and Increased Functional Connectivity in the Frontal Cortex Predict Age-Related Cognitive Dysfunction.

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